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John C. Karpie, MD

Accepting New Patients

John C. Karpie, MD


Orthopedic Surgery

Sports Medicine

Joint Replacement

Shoulder / Elbow Surgery


Buffalo Orthopedic Group
192 Park Club Lane, STE 100
Williamsville, NY 14221

Buffalo Orthopedic Group
4855 Camp Rd., STE 100
Hamburg, NY 14075

Buffalo Orthopedic Group
224 E Main St.
Springville, NY 14141

Buffalo Orthopedic Group
400 N. Main Street
Warsaw, NY 14569


Sisters of Charity Hospital
2157 Main Street
Buffalo, NY 14214

St. Joseph Campus
2605 Harlem Road
Cheektowaga, NY 14225






A native of Williamsville, NY, Dr. Karpie received his medical degree from the University at Buffalo School of Medicine and Biomedical Sciences.

He completed his internship in general surgery and his residency in orthopaedic surgery at the University of Pittsburgh Medical Center (UPMC), where he also worked as an attending orthopedic trauma surgeon.

Board certified in orhtopedic surgery, Dr. Karpie worked as a clinical instructor and general orthopaedist at the VA Healthcare system in Pittsburgh PA, where he performed a number of orthopaedic procedures including ACL reconstructions, rotator cuff repairs, and hip and knee replacements on our nation’s veterans of foreign wars.

He completed a fellowship in orthopaedic sports medicine at the New England Baptist Hospital in Boston MA, served as assistant team physician for the NBA’s Boston Celtics., was a clinical instructor at Tuft’s University School of Medicine, and team physician for the Tufts University Jumbos. He also spent time at Boston Children’s Hospital learning comprehensive assessment, treatment and follow-up care to children, adolescents and young adults with sports-related orthopaedic injuries.

Dr. Karpie specializes in the treatment of all sports related orthopaedic injuries, concentrating on the arthroscopic treatment of knee and shoulder disorders, including ACL, meniscus, and cartilage injuries, as well as rotator cuff injuries and shoulder instability. Other interests include comprehensive fracture care, total hip, knee and shoulder replacement surgery.